Search results for "Sleep disordered breathing"

showing 10 items of 21 documents

A Randomized Controlled Trial of Continuous Positive Airway Pressure on Glucose Tolerance in Obese Patients with Obstructive Sleep Apnea

2014

Study objectives Obstructive sleep apnea (OSA) is associated with an increased prevalence of metabolic syndrome (MetS), even in patients with morbid obesity. Our goal was to address whether continuous positive airway pressure (CPAP) treatment improved glucose metabolism in this population. Methods A prospective randomized controlled trial was performed in severe OSA patients with morbid obesity without diabetes in two university referral hospitals. Patients received conservative (CT) versus CPAP treatment for 12 weeks. MetS components, homeostasis model assessment of insulin resistance (HOMA-IR) and oral glucose tolerance were assessed at baseline and after treatment. Results A total of 80 …

AdultBlood GlucoseMalemedicine.medical_specialtyglucose tolerancemedicine.medical_treatmentPopulationSettore MED/10 - Malattie Dell'Apparato Respiratorio030204 cardiovascular system & hematologyImpaired glucose tolerance03 medical and health sciences0302 clinical medicineInsulin resistancePhysiology (medical)Internal medicineDiabetes mellitusinsulin resistanceGlucose IntoleranceWeight LossmedicineHumansInsulinProspective StudiesContinuous positive airway pressureeducationobstructive sleep apneaMetabolic SyndromeSleep Apnea Obstructiveeducation.field_of_studyGlucose tolerance testContinuous Positive Airway Pressuremedicine.diagnostic_testbusiness.industryGlucose Tolerance TestMiddle Agedmedicine.diseaseObesity Morbidrespiratory tract diseasesSurgeryObstructive sleep apnea030228 respiratory systemFemaleNeurology (clinical)Insulin ResistanceMetabolic syndromeSleep Disordered Breathingbusinesscontinuous positive airway pressure
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Automatic bilevel ventilation in sleep-disordered breathing: A real-life experience in southern Italy

2016

Automatic bilevel ventilation (AutoBI) has been recently introduced to treat obstructive sleep-disordered breathing (SDB), but clinical experience is still limited. We revised the charts of patients treated for obstructive SDB in our sleep clinic in 2015 (n=214) to assess the frequency of trials of AutoBI ventilators (ResMed Auto25 or Respironics BiFlex), the clinical characteristics of these patients, the reason to shift from CPAP to AutoBI, and the outcome of AutoBI titration. A trial of domiciliary AutoBI was made in 44 patients (20.5%) intolerant to CPAP due to high CPAP levels (n=11) or who showed incomplete resolution of SDB on CPAP (n=33). The table reports the clinical data accordin…

COPDPediatricsmedicine.medical_specialtyExtreme obesitybusiness.industrymedicine.diseaseAlternative treatmentnervous system diseasesrespiratory tract diseasesBreathingmedicineSleep disordered breathingArterial bloodIn patientbusiness4.2 Sleep and Control of Breathing
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Automatic bilevel ventilation (AutoBI) in obstructive sleep-disordered breathing (SDB): clinical features and compliance to treatment

2017

CPAP is the first-choice treatment for obstructive SDB, but the criteria to prescribe AutoBI are undefined. Trials of AutoBI ventilation in patients under titration for obstructive SDB from January 2015 to January 2017 ((n=67 out of 265 titrations) were reviewed to assess: a) their clinical features, b) the reason to shift from CPAP to AutoBI, and c) long-term compliance to treatment. AutoBI was used in cases of intolerance to high therapeutic CPAP levels (n=23) or incomplete resolution of SDB on CPAP (n=45). AutoBI failed in 11 patients (16.4%): 2 OSA patients (7.7%), 4 overlap patients (21%), and 5 OHS patients (22.7%). The Table reports the differences at diagnosis between patients presc…

Compliance (physiology)business.industryAnesthesiaBreathingSleep disordered breathingMedicineIn patientbusinessnervous system diseasesrespiratory tract diseasesSleep and Control of Breathing
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Long-term variations of arterial stiffness in patients with obesity and obstructive sleep apnea treated with continuous positive airway pressure

2020

BackgroundObstructive sleep apnea (OSA) is associated with cardiovascular co-morbidities and mortality. Arterial stiffness is an independent predictor of cardiovascular risk and mortality, and is influenced by the presence of OSA and related comorbidities. There is a paucity of data regarding long-term evolution of arterial stiffness in CPAP-treated OSA patients. We aimed to prospectively study long term PWV variations and determinants of PWV deterioration.MethodsIn a prospective obese OSA cohort, at time of diagnosis and after several years of follow-up we collected arterial stiffness measured by carotid-femoral pulse wave velocity (PWV), clinical and metabolic parameters, and CPAP adheren…

MalePulmonologyApneaPhysiologymedicine.medical_treatmentBlood PressurePolysomnography030204 cardiovascular system & hematologyVascular Medicine[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tractStiffnessCohort StudiesMedical ConditionsMathematical and Statistical TechniquesEndocrinology0302 clinical medicineRisk FactorsMedicine and Health SciencesContinuous positive airway pressurePulse wave velocitySleep Apnea Obstructiveeducation.field_of_studyMultidisciplinaryContinuous Positive Airway Pressuremedicine.diagnostic_testPharmaceuticsStatisticsQlongitudinal studyRSleep apneaBlood Pressure Monitoring AmbulatoryMiddle Aged[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system3. Good healthCardiovascular TherapyNeurologyPhysiological ParametersCardiovascular DiseasesPhysical SciencesHypertensioncardiovascular systemCardiologysleep disordered breathing.MedicineFemaleResearch Articlecirculatory and respiratory physiologymedicine.medical_specialtySleep ApneaEndocrine Disorderspulse wave velocityPolysomnographyScienceMaterials ScienceMaterial PropertiesPopulationSettore MED/10 - Malattie Dell'Apparato RespiratorioResearch and Analysis MethodsRespiratory Disorders03 medical and health sciencesVascular StiffnessDrug Therapy[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemInternal medicineDiabetes MellitusmedicineMechanical PropertiesHumansObesityStatistical Methodseducationbusiness.industryBody WeightBiology and Life Sciencesmedicine.diseaserespiratory tract diseasesObstructive sleep apneaBlood pressure030228 respiratory systemMetabolic DisordersMultivariate AnalysisArterial stiffness[SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tractSleep DisordersbusinessMathematicsPLOS ONE
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A survey around the Italian pediatric units on current clinical practice for Sleep Disordered Breathing (SDB)

2019

Background During recent years, interest on Sleep Disordered Breathing (SDB) in pediatric age has increased, due to the impact on quality of life, psycho-physical attitude and other serious morbidities if undiagnosed and untreated. Methods Italian Pediatric Respiratory Diseases Society (SIMRI) SDB-Working Group carried out an exploratory survey in Italy, from January to December 2016, to assess the diagnostic and therapeutic pathways, perception and relevance of SDB in Italian Hospitals. Results A questionnaire was sent to 180 Pediatric Units (PUs) distributed throughout the Italy; 102 Pediatric Units (PUs; 56.6%) answered and among them 57% dealt with SDB, and 94% recognized SDB as a major…

Malemedicine.medical_specialtyPractice PatternsPolysomnographyChildren; Italy; Pediatric units; Sleep disordered breathing; Survey; Child; Female; Humans; Italy; Male; Practice Patterns Physicians'; Sleep Apnea Syndromes; Surveys and QuestionnairesChildren; Italy; Pediatric units; Sleep disordered breathing; Survey03 medical and health sciencesExploratory surveySleep Apnea Syndromes0302 clinical medicineQuality of lifeSurveys and Questionnaires030225 pediatricsmental disordersmedicineHumanscardiovascular diseases030212 general & internal medicinePractice Patterns Physicians'ChildPediatric unitsSurveyChildrenPhysicians'medicine.diagnostic_testSleep disordered breathingPediatric respiratory diseasesbusiness.industryResearchlcsh:RJ1-570lcsh:PediatricsPediatric agenervous system diseasesrespiratory tract diseasesNorthern italyClinical PracticeItalyEmergency medicineSleep disordered breathingFemalebusinessItalian Journal of Pediatrics
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Cancer prevalence is increased in females with sleep apnoea: data from the ESADA study

2019

[No abstract available]

MaleobesityLetterDatabases FactualDownload[SDV]Life Sciences [q-bio]cigarette smokingPolysomnographycancer riskdisease burdenapnea hypopnea indexsleep disordered breathingstudy design0302 clinical medicinepolysomnographyRisk FactorsNothingcancer diagnosisNeoplasmsmiddle agedgenderPrevalence030212 general & internal medicineSleep studyobstructive sleep apneaSleep Apnea Obstructiveeducation.field_of_studyanthropometryquantitative analysismedicine.diagnostic_testadultrisk assessmentclinical trialcohort analysisprostate cancerpulse oximetry[SDV] Life Sciences [q-bio]Europenot availablecomorbidityagedfemalewaist hip ratiocolon cancerpriority journalrisk factorfactual databasedisease severitycerebrovascular accidentPulmonary and Respiratory Medicinemedicine.medical_specialtyalcohol consumptionintermittent hypoxiaPopulationMEDLINElymphomaSettore MED/10 - Malattie Dell'Apparato Respiratoriomalignant neoplasmcancer growth03 medical and health sciencesmelanomamedicinecancercross-sectional studyHumanscontrolled studyhumaneducationCancer prevalencehypoxiabusiness.industrystatistical modelConflict of interestpredictionmajor clinical studybody massoxygen saturationlung cancermulticenter studyCross-Sectional StudiesLogistic Modelsage030228 respiratory systemdisease severity assessmentFamily medicineoxygen desaturation indexhead and neck cancerHuman medicinebusinessneoplasmEuropean Respiratory Journal
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Role of menopause and hormone replacement therapy in sleep-disordered breathing

2020

There are suggestions that the loss of female sex hormones following menopause is critical for the development or progression of sleep-disordered breathing (SDB). We conducted a review of the literature on the role of menopause and hormone replacement therapy (HRT) in SDB risk. There is an increase in SDB during the menopausal transition period, but data on an effect beyond that of increasing age and changes in body habitus are weak or absent. Early community-based, observational studies reported a protective effect by HRT on SDB prevalence, but this could possibly be explained as a healthy user effect. Interventional studies of the effect of HRT on SDB are sparse, with only a few randomize…

Pulmonary and Respiratory MedicinePediatricsmedicine.medical_specialtymedicine.drug_classSettore MED/10 - Malattie Dell'Apparato Respiratorio03 medical and health sciencesSleep Apnea Syndromes0302 clinical medicineWomanPhysiology (medical)mental disordersPrevalenceHumansMedicineObesitycardiovascular diseasesSleep-disordered breathingbusiness.industrymedicine.diseaseEstrogenObstructive sleep apneaObesitynervous system diseasesrespiratory tract diseasesObstructive sleep apneaMenopauseMetabolismHormone replacement therapy030228 respiratory systemNeurologyEstrogenTransgender hormone therapySleep disordered breathingFemaleObservational studysense organsNeurology (clinical)Menopausebusiness030217 neurology & neurosurgeryHormoneSleep Medicine Reviews
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Comment to the Editorial by KS Park and EW Kang “Is only fixed positive airway pressure a robust tool for kidney protection in patients with obstruct…

2019

We thank doctors Park and Kang for their editorial that well summarized our article. Our common belief is that one of the possible consequences of untreated obstructive sleep apnea (OSA) is an accelerated deterioration of kidney function, and that more knowledge would be necessary on the possible protective effects of OSA treatments. To our knowledge, so far the only OSA therapy whose effects on renal function have been tested is continuous positive airway pressure (CPAP), and most , although not all studies, have demonstrated its benefits. Our own study, while confirming benefits of fixed CPAP, has demonstrated little effect of auto-adjusting CPAP (APAP). This finding may be of relevance a…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyLetterestimated glomerular filtration ratekidney diseaseRenal functionPolysomnographySettore MED/10 - Malattie Dell'Apparato Respiratoriosleep disordered breathingpolysomnographyrenal protectionPositive airway pressureMedicineIn patienthumansleepIntensive care medicinekidney functionLetter to the EditorPositive end-expiratory pressureKidneymedicine.diagnostic_testbusiness.industryobstructive sleep apnea ; kidney protection ; fixed positive airway pressuremedicine.diseaseoxygen saturationrespiratory tract diseasesObstructive sleep apneaNot availablemedicine.anatomical_structureEditorialpositive end expiratory pressureHuman medicinebusinesschronic obstructive lung diseaseKidney disease
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EAN/ERS/ESO/ESRS statement on the impact of sleep disorders on risk and outcome of stroke.

2020

BACKGROUND Sleep disorders are highly prevalent in the general population and may be linked in a bidirectional fashion to stroke, which is one of the leading causes of morbidity and mortality. AIM Four major scientific societies established a task force of experts in neurology, stroke, respiratory medicine, sleep medicine and methodology to critically evaluate the evidence regarding potential links and the impact of therapy. MATERIALS AND METHODS Thirteen research questions were evaluated in a systematic literature search using a stepwise hierarchical approach: first, systematic reviews and meta-analyses; second, primary studies post-dating the systematic reviews/meta-analyses. A total of 4…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyPeriodic limb movement disorderNeurologymedicine.medical_treatmentinsomniaPopulationsleep apnea RLS insomnia strokerestless legs030204 cardiovascular system & hematologySettore MED/10 - Malattie Dell'Apparato RespiratorioSleep medicine03 medical and health sciencessleep disordered breathing0302 clinical medicineRestless Legs SyndromeSleep Initiation and Maintenance DisordersInsomniamedicinePrevalenceinsomnia outcome PLMS restless legs risk sleep disordered breathing sleep disorders strokeHumansContinuous positive airway pressure030212 general & internal medicineRisk factoreducationIntensive care medicinePLMSStrokeriskeducation.field_of_studySleep disorderSleep Apnea ObstructiveContinuous Positive Airway Pressurebusiness.industryMiddle Agedmedicine.diseasestrokeStrokeSystematic reviewNeurologyMeta-analysisoutcomesleep disordersNeurology (clinical)medicine.symptombusiness030217 neurology & neurosurgeryThe European respiratory journal
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Sleep HERMES: a European Core Syllabus in respiratory disorders during sleep.

2011

The clinical characterisation and description of the obstructive sleep apnoea–hypopnoea syndrome (OSAHS) and related syndromes were mainly revealed by several epidemiological studies conducted over the past fifty years. These highly prevalent syndromes affect about 9% of middle-aged men and 4% of women. These syndromes have serious medical and social consequences, such as cardiovascular or metabolic diseases, and even premature death. Consequently, respiratory sleep medicine (RSM) evolved and has progressed rapidly within the sleep medicine field over recent decades. New diagnostic and therapeutic techniques have appeared in response to an increasing number of patients and clinical interven…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyTeaching program; sleep disordered breathingTeaching programPsychological interventionCertificationBiologySettore MED/10 - Malattie Dell'Apparato RespiratorioSleep medicineSyllabusRespiratory Medicinesleep disordered breathingDocumentationFamily medicineEpidemiologymedicineSleep (system call)Human medicine
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